As an institutional member of ISQua, ACSIS embraced the global dialogue at the 41st ISQua International Conference held in vibrant São Paulo, Brazil from 12 to 15 October 2025. In that dynamic urban canvas of innovation and culture, the conference’s theme of “Inclusive Health Systems: Navigating Challenges with Technology and Humanity” set the tone for meaningful exchange between health-care practitioners, policymakers, patient advocates and systems designers. ACSIS’s team immersed themselves in workshops, plenary dialogues and networking forums, sharing insights from Ethiopia’s journey of strengthening maternal, reproductive and primary care systems through evidence, co-production and innovation. With each conversation, ACSIS emphasized its commitment to ensuring that health care is not only safe and effective, but also equitable, person-centered and resilient in the face of rapid technological change and complex system demands.